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rosuvastatin (CRESTOR) A comprehensive review of the safety and effectiveness of this drug. If the drug is not a Do Not Use product, information on adverse effects, drug interactions and how to use the medication are included.The evidence for treatment, especially with cholesterol-lowering drugs, is much weaker for people who have not yet had the cardiovascular disease described above, known as primary prevention. This is especially so for those people who do not have more than one of the following risk factors: hypertension, diabetes, smoking, obesity, or a close family history of premature heart attacks or strokes. CRESTOR� (rosuvastatin calcium) Clinical Experience Lowering LDL-C: Switching Therapy Comparative Data . We invite you to consider the trial information presented here when selecting a statin treatment option for your appropriate at-risk patients.Based upon the results of the JUPITER trial, CRESTOR is indicated in patients without clinically evident coronary heart disease (CHD), to reduce the risk of myocardial infarction, stroke, and arterial revascularization in men ?50 years and women ?60 years with hsCRP ?2mg/L and at least one additional cardiovascular disease (CVD) risk factor. Crestor: 118 user reviews - DailyStrength Join | Help | Sign In 0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z Crestorqf6 (Crestorqf6) | Formspring Your question has been sent to Crestorqf6. Ask another. Smiled at... Public Questions Crestor User Reviews for High Cholesterol at Drugs.com A B C D E F G H I J K L M N O P Q R S T U V W X Y Z Advanced Phonetic Started on Crestor 5 mg a year and a half ago. It immediately lowered my Cholesterol by 60 points. No problems until 4 months ago. Started having heart palpitations, mainly at night which is when I took the Crestor. They got so severe, I would be up all night. After doing a lot of researching on the internet, I found that other people had experienced this too, so I stopped the medicine and haven't had any palpitations since. My doc seems reluctant to believe this was the cause.Crestor Safe and Effective When Used According to Prescribing InformationConclusions from a review published in Circulation today regarding CRESTOR are misleading, and unfortunately create unnecessary alarm for patients who need this medication to lower their cholesterol. The FDA has access to the most complete data set and according to their conclusion, "[o]ur review of all of the available evidence (including preclinical data, pre-marketing clinical studies, Phase 4 clinical studies, and post-marketing adverse event reports) indicates that CRESTOR does not pose a risk of muscle toxicity greater than the other approved statins, and that with respect to renal toxicity, there is no convincing evidence that CRESTOR poses a risk of serious renal injury." CRESTOR is contraindicated in patients with active liver disease or unexplained persistent elevations of serum transaminases, in women who are pregnant or may become pregnant, and in nursing mothers. It is recommended that liver function tests be performed before and at 12 weeks following both the initiation of therapy and any elevation of dose, and periodically (e.g., semiannually) thereafter. Rare cases of rhabdomyolysis with acute renal failure secondary to myoglobinuria have been reported with CRESTOR and with other drugs in this class.
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